製薬機械(装置)

Multiple Effect Type Stills

Features

This still designed to meet to USP specification of water for injection, meantime acording to water quality differ from feed water and different number of effects, the distillate resistivity quality easy to obtain and the distillate temperature id over 80°C to avoid bacteria growing. The feed water at least is better than Deionized Water (DIW).

Cooling Exchanger / According FDA

Construction

  • Machine contacting feed-water part all using SUS 316L stainless steel 320-340# grit polish.
  • Double tube sheet design, free from cooling water cont amination into distillations by glass fiber.
  • Exterior support and flanges by SUS 304.
  • Before running all piping passivation process.

Procedure

This equipment is take advantage of heat exchanger working principle, just first column is heated by an extermal steam, other column is from the first column pure steam used for heating the next column, use evaporator and condenser to force the proceed two phase variation, detailed describing as following.

First, let evaporator inside feed water pass through heat exchanger change from liquid to vapor, use its latent heat into separator. In the separator inside is equip with special mist damper and high centrifugal force cyclone dervice. The vapor will passing through 180 degree continuous rotation, by means of above mentioned special dervice to separate particles, drops and pyrogenic, and so on the vapor of leaving separator is not contains solution solid and pyrogenic, it is sterile and pryogenation free. These particles and drops will return to the evaporator column low part to hearting again, here just high speed purified vapor can pass through the separator enter condenser. Then to processed second phase variation, let condenser inside vapor pass through cooling exchanger change from vapor to liquid (distillate), and use diverter valve to assure the distilled water quality, if the water quality is below purity set, it will exhaust to drain piping, otherwise it will flow to storage tank to provide with the pharmaceutical purpose of water for injection.

Moreover, due to this still is adopt multiple effect type and via first condenser to preheat the feed water before entering each column, meanwhile every column the evaporation inside feed water latent heat piping device is equip with recovery, to consumption of the steam energy.

Procedure Chart

Specifications:

Mode
Number of
Effects
5 Bar Steam Heating
Dimensions
Production
Capacity (Lt/hr)
Steam
(kg/r)
Cooling
Water (Lt/hr)
Height
(mm)
Length
(mm)
Width
(mm)
Weight
(mm)
MS-250/4
4
250
85
280
280
2,500
1,300
800
MS-500/4
4
510
150
500
500
2,500
1,300
900
MS-500/5
5
510
130
300
300
2,500
1,450
1,000
MS-1000/5
5
1,200
320
600
600
2,900
1,900
2,000
MS-1000/6
6
1,200
270
600
600
2,900
2,240
2,300
MS-1500/5
5
1,700
420
750
750
3,200
3,040
2,700
MS-1500/6
6
1,700
350
750
750
3,200
3,350
3,000
MS-2000/5
5
2,200
620
1,000
1,000
3,200
3,000
3,300
MS-2000/6
6
2,200
550
1,000
1,000
3,200
3,430
3,800
MS-3000/6
6
3,200
700
1,200
1,200
3,700
3,900
4,800
MS-4000/6
6
4,300
1,000
1,400
1,400
3,900
4,480
6,800